Early Antibiotic Use May Affect on Child Development

Early Antibiotic Use May Affect on Child Development

According to a new study, published in Nature Communications, antibiotic in early childhood can be responsible for: increased bone growth, weight gain and change gut bacteria. Dr. Martin Blaser, from the NYU Langone Medical Center, in the United States, in 2011, 262 million courses of antibiotics were prescribed. According to this researcher, the antibiotic use is the highest among children under the age of 10. An average child in the US, receives 3 courses of antibiotics by the age of 2 and 10 courses by the age of 10.
There were several previous studies. All of them found that early antibiotic use may affect on a child’s health. A study from 2014 found that early antibiotic use (before age of 2) can cause obesity in early childhood. Another study found that antibiotics can increase risk of juvenile idiopathic arthritis.
However, these studies were conducted on animals. They used low-dose of antibiotics. But, humans receive much higher dosages. Some of them are between 10 and 100 times higher. So, previous studies may be irrelevant.
During this study, the team gave young mice (female) 3 shots of: tylosin and amoxicillin. They are common antibiotics. The mice received the same dosages as a child at the age of 2. These mice were compared with a group of mice that didn’t receive antibiotics. Researchers found that antibiotics led to larger bones, weight gain and altered gut bacteria.
These findings suggest that tylosin has a higher impact on gut bacteria than amoxicillin. They also found that altered gut bacteria had a much lover ability to adapt to potential changes.